Guglielmo Plüschow (born Wilhelm Plüschow ; August 18, 1852 – January 3, 1930), was a German photographer who moved to Italy and became known for his nude photos of local youths, predominantly males. Plüschow was a cousin of Wilhelm von Gloeden , who, despite taking up nude photography later than Plüschow, soon overshadowed him. Plüschow was several times at odds with the law and charged with corruption of minors. Today, his photography is recognized for its artistic merits, even though it is generally considered somewhat inferior to Gloeden's on account of his less graceful handling of lighting and the sometimes strangely stilted poses of his models.

Not much is known about Plüschow's early life, except that he was born in Wismar as the eldest of seven brothers and sisters. His father Friedrich Carl Eduard Plüschow was an illegitimate child of Frederick Louis, Hereditary Grand Duke of Mecklenburg-Schwerin and the family home was Schloss Plüschow .

In the early 1870s, he moved to Rome and changed his first name from "Wilhelm" to its Italian equivalent "Guglielmo". Initially making a living as a wine merchant, he soon turned to male and female nude photography . Later he also worked in Naples .